Capture pathogens. Physically remove them.

PCT is a technology from Aquila Bioscience that captures viruses, bacteria, fungi, spores and biotoxins and removes them, rather than killing them with chemicals.

How it works, in three steps

  1. 1

    A pathogen approaches a human cell and looks for a sugar to bind to.

  2. 2

    PCT presents a decoy target, so the pathogen binds to the product instead of the person.

  3. 3

    The captured pathogen leaves with the wipe, dressing or filter — with no chemical action.

Borrowed from the body's own defences

Tears, mucus and milk use sugar structures — glycans — to trap microbes. PCT applies the same recognition principle to a manufacturable material, choosing the sugar for the target pathogen.

Read the glycobiology
Multivalent binding: many glycan contacts hold one pathogen. Figure: Aquila Bioscience.

Follow one pathogen through capture

Step through the four stages of the PCT mechanism. Use the buttons, or the arrow keys when the explorer has focus.

  1. 1/4 Recognition

    Pathogens infect by binding to carbohydrates on the surface of human cells. PCT presents engineered glycan structures selected for the target pathogen, so the pathogen recognises the product as a binding site.

Diagram of multivalent binding between pathogen surface proteins and branched glycan structures on a bio-functionalised material

Conceptual visualization — not a literal molecular model.

Mode of action, side by side

Traditional antimicrobials

  • Attack and kill organisms chemically
  • Leave debris behind
  • Chemical pressure that pathogens can adapt to

Pathogen Capture Technology

  • Captures and removes organisms physically
  • Pathogen leaves with the product
  • Nothing is chemically attacked, so resistance is not created

Built into the formats you already make

Aquila supplies the ingredient and technical support; partners make the final product. PCT is usually added at an existing process step.

  • Wipes
  • Gels and serums
  • Sprays
  • Rinses and washes
  • Coatings and paints
  • Filters
  • Dressings
  • Medical devices such as swabs

Where the confidence comes from

14+ years
of R&D that began at the University of Galway, before the 2012 spin-out
30+ pathogens
evaluated through independent laboratory testing
Human skin explant study
conducted in France
Patents
including WO 2020/240027 A1

Research programme

Bring PCT into your product or programme.

Tell us your target pathogen, your product format or your field challenge. Thirty minutes with the science team is enough to know whether PCT is the right fit before you commit to anything.